About

History

The Gates Biomanufacturing Facility (GBF) is a partnership among the Gates Center, University of Colorado Anschutz Medical Campus, University of Colorado School of Medicine, Children’s Hospital Colorado, University of Colorado Health and the Gates Frontiers Fund.

Generous gifts from the private sector totaling $8.5 million covered renovation and equipment costs, and partner institutions below are each contributing toward operating costs.

The Gates Biomanufacturing Facility (GBF) held its Grand Opening on April 6, 2015. The GBF is operated by the Gates Center for Regenerative Medicine at the University of Colorado School of Medicine.

Partners

University of Colorado Health
University of Colorado School of Medicine
Children’s Hospital Colorado
University of Colorado Anschutz Medical Campus
Gates Frontiers Fund

GBF Team

Gates Biomanufacturing Facility Team

From Left to Right – Rebecca Vartuli, Kaela Siahpush, Russell Marians, Sadhna Mehra, Deepa Vadakkan, Renee Jesser, Mitchell Fraller, Bailey Leadford, Sonja Giguere, Heather Clark, Tim Gardner, David Hahn, Frances Brostrom, Paul Lemaire, Jackie Nelson, Matt Seefeldt, Juan Mantalvo, Carter Sarah, Bertina Minjares, Graciela Gamez, Felicia Lanzarone, Christopher Freedman, Jaclyn Valentine, Debbie Keenan, Jessica Freeman, Saundra Jernberg, Tom Street

Management Team


Terri Foote

DIRECTOR, PROGRAM MANAGEMENT AND SUPPLY CHAIN

  • 20+ years’ experience in the pharmaceutical industry, holding various leadership positions in Supply Chain, Program Management, Operations, Sales and Business Development, and Engineering
  • Former Vice President of Technical and Business Operations at Tolmar, Inc., a pharmaceutical company with a legacy and pipeline in extended release dosage forms commonly used in oncology and urology, along with an extensive portfolio of dermatology products
  • Former Head of Global Manufacturing Supply Chain for Sandoz, the generic division of Novartis Pharmaceuticals Inc. with responsibility for establishing harmonized global supply chain organizations, processes, and performance across 25 internal manufacturing sites, 10 global 3rd party suppliers, and 65 different Sandoz/Novartis country sales and marketing organizations
  • Certified Project Management Professional (PMP) with over 10 years project and program management, including multiple Phase 1 and software implementation projects
  • Certified executive coach, leadership trainer, and speaker; mentorship member through The John Maxwell Team
  • B.S. in Industrial Engineering from University of Nebraska.  Executive M.B.A. from University of Colorado

Charles Hickey

DIRECTOR OF FINANCE AND OPERATIONS

  • 20 years of financial experience with over 15 years specifically in the manufacturing industry
  • Joined the GBF team in September of 2020 as Director of Finance and Administration
  • Former Controller/CFO for a mid-sized Colorado Springs Biomanufacturing company, growing the business to over 200 employees
  • Former Sr. Financial Controller for Evoqua Water Technologies a division of Siemens Industry that spun off and relisted on the NASDAQ in Jan 2016 (AUQUA)
  • Former Cost Accounting Manager for Ingersoll Rand’s – Climate Control Division in St. Louis, where he led cost accounting for a multi-million-dollar manufacture of specialty refrigeration equipment (Hussmann)
  • Former Financial Manager for GE Aviation’s MRO & FBO business providing variety of specialization in cost accounting, inventory control and financial reporting
  • Former Chief Fiscal Officer for the City of St. Louis Department of Health and Hospitals
  • Former Fiscal Manager for the City of St. Louis Office of Budget and Management responsible for Public Safety funding in the City of St. Louis
  • Bachelor of Science in Finance and Business Economics from Southern Illinois University, and a Master’s in Finance from the University of Missouri

Roger Giller, M.D.Roger Giller, M.D.

MEDICAL DIRECTOR

  • Over 30 years of experience in laboratory research, clinical research and patient care in the fields of human bone marrow transplantation and other forms of cellular therapy
  • Founded, then led and maintained regulatory compliance of the Pediatric Bone Marrow Transplant Program at Children’s Hospital Colorado / University of Colorado School of Medicine for 23 years (1993 – 2016)
  • Extensive patient care and clinical research expertise in hematopoietic stem cell transplantation, pediatric cancer, nonmalignant blood diseases and immunologic disorders

Matthew Seefeldt, PhDMatthew Seefeldt, Ph.D.

EXECUTIVE DIRECTOR

  • Eighteen years of experience in biotechnology manufacturing, with an emphasis on translating early-stage therapeutics into the clinic
  • Developed six IND-enabling cGMP processes on both microbial derived proteins and cell therapy products. One of those products was successfully scaled to support Phase III clinical studies
  • Successfully completed the build out and GMP preparation of the Gates Biomanufacturing Facility
  • Considered a world expert in protein refolding
  • Expert in protein stability and formulation, with specific understanding of the link between aggregates and immunogenicity

 

Chandresh Undhad, M.S.

ASSOCIATE DIRECTOR, QUALITY – GATES BIOMANUFACTURING FACILITY

  • Joined GBF as Quality Assurance Manager in 2019
  • Leads the quality strategy for GBF’s growing portfolio of products and brings a wealth of experience across therapeutic modalities, including cell therapy and biologics
  • Former experience at Memorial Sloan Kettering Cancer Center, where Chandresh spent his career in various roles including Cell Therapy product development but most noticeably building quality system for early-stage Cell Therapy products, products which were critical for the center’s mission to provide treatment option to patients with unmet needs
  • Master’s degree in Pharmacology as well as a Bachelor’s degree in Pharmacy

 

Gana Batt, Ph.D.

ASSOCIATE DIRECTOR OF PROTEIN DEVELOPMENT AND MANUFACTURING

  • 10+ years’ experience in recombinant protein expression and purification, protein folding and stability
  • Coupling, troubleshooting, and optimization of custom ligand columns for protein purification
  • Assay development for protein-protein, protein-ligand, and enzyme-substrate interactions
  • Biological functional activity and immunological reactivity assay optimization
  • Microbial culturing and scale-up, purification of biologics used for medical device manufacturing
  • Process development, technology transfer to manufacturing and continuous improvement
  • Authored numerous standard operating procedures and master batch records
  • Competent leader and supportive mentor building a team focused on efficiency and productivity, promoting values for professional growth and development
  • B.S in Biology and M.S. in Biophysics from Lomonosov Moscow State University, Ph.D. in Biochemistry and Molecular Biology from Virginia Polytechnic Institute and State University